Revascularization Strategy for Proximal LAD Disease

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Revascularization Strategy for Proximal LAD Disease

SEE PAGE 2717 S ignificant proximal left anterior descending artery (LAD) disease may jeopardize up to 50% of the left ventricular myocardium (1) and predicts worse outcomes (2), with a significantly worse 5-year patient survival rate (90% vs. 98%) than downstream LAD lesions (3). In the 1990s, randomized controlled trials (RCTs) showed that all treatment modalities, namely, medical therapy, pe...

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In stable patients with multivessel coronary artery disease (CAD), coronary bypass operation (coronary artery bypass grafting [CABG]) has been found to be superior to percutaneous coronary intervention (PCI) using drug-eluting stents (DES) [1–3]. The finding is based on wellpowered randomized studies [4,5] and large-scale registries [6,7]. The superiority of CABG is demonstrated by lower shorta...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2014

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2014.10.019